Losartan - Drug Details

Losartan (Cozaar)

Classification

Angiotensin II Receptor Blocker (ARB)

Mechanism of Action

Indications

Hypertension, diabetic nephropathy

Dosage and Administration

50-100 mg once daily, may be divided into two doses.

Forms

Tablet

Side Effects

Dizziness, back pain, nasal congestion

Contraindications

Pregnancy, severe renal impairment

Interactions

May increase blood potassium levels when taken with potassium supplements or potassium-sparing diuretics

Precautions

Monitor blood pressure and renal function

Pharmacokinetics

Absorbed orally, metabolized in the liver, excreted in urine and feces

Pharmacodynamics

Reduces blood pressure, slows progression of kidney disease in diabetics

Storage Requirements

Store at room temperature, protect from light and moisture

Patient Counselling

Avoid salt substitutes containing potassium unless advised by your doctor

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