Simvastatin - Drug Details

Simvastatin (Zocor)

Classification

Statin, HMG-CoA Reductase Inhibitor

Mechanism of Action

Indications

Hypercholesterolemia, hypertriglyceridemia

Dosage and Administration

10-40 mg once daily in the evening

Forms

Tablet

Side Effects

Muscle pain, constipation, nausea

Contraindications

Active liver disease, pregnancy, breastfeeding

Interactions

Increased risk of myopathy with other lipid-lowering drugs

Precautions

Monitor liver enzymes before and during therapy

Pharmacokinetics

Absorbed orally, metabolized by the liver, excreted in bile

Pharmacodynamics

Lowers LDL cholesterol, raises HDL cholesterol

Storage Requirements

Store at room temperature, away from moisture and heat

Patient Counselling

Report any unexplained muscle pain or weakness to your doctor immediately

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