Metoprolol - Drug Details

Metoprolol (Lopressor, Toprol XL)

Classification

Beta-Blocker

Mechanism of Action

Indications

Hypertension, angina, heart failure, myocardial infarction

Dosage and Administration

25-100 mg once daily or in divided doses, depending on the condition.

Forms

Tablet, extended-release tablet

Side Effects

Bradycardia, fatigue, dizziness, depression

Contraindications

Severe bradycardia, heart block greater than first degree

Interactions

Increased risk of bradycardia with other beta-blockers

Precautions

Monitor heart rate and blood pressure regularly

Pharmacokinetics

Well absorbed, metabolized in the liver, excreted by the kidneys

Pharmacodynamics

Reduces heart rate, myocardial contractility, and blood pressure

Storage Requirements

Store at room temperature, away from light and moisture

Patient Counselling

Take with or immediately after meals

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