Atorvastatin - Drug Details

Atorvastatin (Lipitor)

Classification

Statin, HMG-CoA Reductase Inhibitor

Mechanism of Action

Indications

Hypercholesterolemia, prevention of cardiovascular disease

Dosage and Administration

10-80 mg once daily, depending on the response and tolerance.

Forms

Tablet

Side Effects

Muscle pain, diarrhea, nasopharyngitis

Contraindications

Active liver disease, pregnancy, breastfeeding

Interactions

Increased risk of myopathy with certain drugs (e.g., fibrates)

Precautions

Monitor liver function tests before and during treatment

Pharmacokinetics

Absorbed orally, extensively metabolized by the liver, excreted in bile

Pharmacodynamics

Reduces cholesterol levels, improves lipid profile

Storage Requirements

Store at room temperature, protect from moisture

Patient Counselling

Avoid grapefruit and grapefruit juice while taking this medication

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