Omeprazole - Drug Details

Omeprazole (Prilosec)

Classification

Proton pump inhibitor

Mechanism of Action

Indications

GERD, peptic ulcer disease, Zollinger-Ellison syndrome

Dosage and Administration

20-40 mg orally once daily

Forms

Capsules, tablets

Side Effects

Headache, diarrhea, abdominal pain

Contraindications

Hypersensitivity to other PPIs

Interactions

May interact with drugs requiring acidic pH for absorption

Precautions

Use the lowest effective dose for the shortest duration

Pharmacokinetics

Half-life: 0.5-1 hour, extensively metabolized in the liver

Pharmacodynamics

Inhibits the final step of acid production

Storage Requirements

Store at room temperature, protect from moisture

Patient Counselling

Take before meals, swallow capsules whole without crushing

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