Gabapentin - Drug Details

Gabapentin (Neurontin)

Classification

Anticonvulsant, GABA analog

Mechanism of Action

Indications

Epilepsy, neuropathic pain

Dosage and Administration

300-600 mg orally three times daily

Forms

Capsules, tablets, solution

Side Effects

Dizziness, drowsiness, peripheral edema

Contraindications

Hypersensitivity to gabapentin

Interactions

May enhance the sedative effects of CNS depressants

Precautions

Use caution in patients with renal impairment

Pharmacokinetics

Half-life: 5-7 hours, excreted unchanged in urine

Pharmacodynamics

Modulates synaptic and nonsynaptic voltage-gated calcium channels

Storage Requirements

Store at room temperature

Patient Counselling

Take as prescribed, avoid abrupt discontinuation

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