Rivaroxaban - Drug Details

Rivaroxaban (Xarelto)

Classification

Anticoagulant, factor Xa inhibitor

Mechanism of Action

Indications

Deep vein thrombosis, pulmonary embolism, stroke prevention in atrial fibrillation

Dosage and Administration

10-20 mg orally once daily

Forms

Tablets

Side Effects

Bleeding, anemia, nausea

Contraindications

Active bleeding, severe renal impairment

Interactions

Avoid concomitant use with other anticoagulants

Precautions

Monitor for signs of bleeding, adjust dose in renal impairment

Pharmacokinetics

Half-life: 5-13 hours, metabolized in the liver

Pharmacodynamics

Prevents clot formation by inhibiting factor Xa

Storage Requirements

Store at room temperature

Patient Counselling

Take with food, monitor for signs of unusual bleeding

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