Alprazolam - Drug Details

Alprazolam (Xanax)

Classification

Benzodiazepine

Mechanism of Action

Indications

Anxiety disorders, panic disorder

Dosage and Administration

0.25-0.5 mg orally three times daily

Forms

Tablets, extended-release tablets

Side Effects

Drowsiness, dizziness, dry mouth

Contraindications

Severe respiratory insufficiency, acute narrow-angle glaucoma

Interactions

Caution with other CNS depressants

Precautions

Use caution in patients with a history of substance abuse

Pharmacokinetics

Half-life: 11.2 hours, metabolized in the liver

Pharmacodynamics

Enhances GABAergic neurotransmission

Storage Requirements

Store at room temperature, protect from light

Patient Counselling

Avoid alcohol, may cause sedation and impair ability to drive or operate machinery

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