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Levothyroxine - Drug Details

Levothyroxine (Synthroid, Levoxyl)

Classification
Thyroid Hormone Replacement
Mechanism of Action
Indications
Hypothyroidism
Dosage and Administration
25-200 mcg once daily, depending on the patients thyroid levels
Forms
Tablet, capsule, injection
Side Effects
Palpitations, weight loss, insomnia
Contraindications
Untreated thyrotoxicosis, acute myocardial infarction
Interactions
May alter the effects of antidiabetic drugs, anticoagulants
Precautions
Monitor thyroid function tests regularly
Pharmacokinetics
Absorbed in the intestines, metabolized to T3 in the liver and other tissues, excreted in urine
Pharmacodynamics
Replaces or supplements thyroid hormone
Storage Requirements
Store at room temperature, protect from light
Patient Counselling
Take on an empty stomach, 30 minutes before breakfast
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